RESULTS: Spiral CT angiograms were of satisfactory diagnostic quality in all 149 patients. Bronchial tree, lobular division and blood vessels of the pig lung. The positive predictive value for CT1 was less than that of CT3 (p = 0.014) owing to the greater number of false positive for CT1. [1, 2] In 1922, Wharton and Pierson reported the first radiographic description of PE. After embolization spiral CT (3 mm and 1 mm collimation), and pulmonary angiography were performed. However, our study design was not intended for such a comparison. However, the ability of spiral CT to detect subsegmental-sized emboli has not been tested. This study has limitations that are intrinsic to the experimental design. In comparison to pulmonary angiography it is less invasive, less expensive, and its use may be more acceptable to physicians (7). CT angiogram of whole chest delivers more radiation than pulmonary angiogram only. In this study the image quality was optimized by maintaining apnea throughout the acquisition of the image. Comparison of the mean sensitivity of the three imaging modalities (Table 1, Figure 1) showed that there was no difference between CT3, CT1, and angiography (p = 0.42). The average rate of injection was 14 ml/ s, and the total dose was 28 ml. Therefore, we have adopted a per embolus experimental design for pragmatic reasons. Within the last several years, spiral computed tomography angiography (SCTA) of the pulmonary arteries has emerged as a noninvasive angiographic modality for the evaluation of patients with suspected pulmonary embolism (PE). * Re:pulmonary embolism #1996584 : mahna - 01/14/10 23:16 : no !!!!! In this study angiography was performed only after main pulmonary artery injection of contrast material. To corrode the tissue surrounding the cast, the lungs were immersed in a solution of supersaturated potassium hydroxide (300 g/L water) for approximately 3 to 4 d. To determine the effectiveness of the cast as an independent gold standard for diagnosing emboli, the number of emboli recovered was calculated as a percentage of the number injected. However, our emboli were made so that they would lodge in branches of the major trunk which are the same size (3.8 to 4.2 mm) as human subsegmental pulmonary arteries (14). On completion of the surgery, emboli were injected and the pigs were transferred to the imaging suites of our institution. Because there is no reason that the differences in anatomy between pigs and humans should favor improved accuracy of one technique in one species, we do not think that this difference in anatomy influences our major conclusions. There was no difference in positive predictive values between CT3, CT1, and angiography (p = 0.25, p = 0.23, respectively). This site needs JavaScript to work properly. Although CT1 was more sensitive than CT3, its positive predictive value was less than CT3 or angiography owing to a greater prevalence of false positives. Pulmonary embolism: diagnosis with spiral CT and ventilation-perfusion scanning--correlation with pulmonary angiographic results or clinical outcome. This potential problem will be minimized with the advent of multidetector CT which will shorten the acquisition time. If the lungs are working properly, the air flow seen on the ventilation scan will match the blood flow seen on the perfusion scan. Spiral computed tomographic (CT) angiography of the pulmonary circulation has emerged recently as a potential useful diagnostic method for the evaluation of the pulmonary circulation. In this study, the sensitivity was 69% and specificity was 84%. Pulmonary angiography is a test to see how blood flows through the lung. 1998 Jul;208(1):201-8. doi: 10.1148/radiology.208.1.9646814. Spiral CT scan of case 2. *The number of false negatives or positives that were identical for both readers is shown in parentheses. Radiol Bras. The results of this study show that in this animal model, spiral CT is comparable to pulmonary angiography for the detection of pulmonary emboli. Background: Spiral computed tomography (CT) has emerged as a potentially conclusive diagnostic test to exclude pulmonary embolism (PE) in patients with non‐high probability scintigraphy and is already widely used—sometimes as the sole primary diagnostic test in the diagnosis of suspected PE.Its true sensitivity and specificity has, however, not been evaluated previously in a …  |  PURPOSE: To evaluate the accuracy of spiral computed tomography (CT) in the noninvasive diagnosis of pulmonary embolism (PE). Images were obtained while pigs were in the supine position. 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